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The resemblance is clear in House’s reliance on inductive reasoning and psychology, even where it might not seem obviously relevant, and his reluctance to just accept circumstances he finds uninteresting. House’s investigatory technique is to remove diagnoses logically as they House & Home Improvement News are proved inconceivable; Holmes uses an analogous technique. Both characters play instruments (House plays the piano, the guitar, and the harmonica; Holmes, the violin) and take drugs (House relies on Vicodin; Holmes makes use of cocaine recreationally).